Metabolic syndrome

Medications for the treatment of high blood pressure: Hypertension (high blood pressure) is a common concomitant of metabolic syndrome, which is why antihypertensive therapy is necessary in many patients. Depending on the presence of underlying diseases and injuries, it is selected individually with some of the most commonly prescribed drugs belonging to the beta-blocker group (metoprolol, nebivolol, atenolol), ACE inhibitors (enalapril, perindopril, trandolapril) with or without combination with a suitable diuretic (hydrochlorothiazide, furosemide, indapamide). In patients with diabetes or existing renal insufficiency, ACE inhibitors or sartans are often preferred due to their nephroprotective effect and benefits in proteinuria.

Prothrombotic drugs and coagulation disorders. One of the most commonly prescribed medications to prevent thrombotic events is low-dose aspirin. At the discretion of the attending physician and depending on the results of laboratory tests, treatment with appropriate anticoagulants (for example, acenocoumarol) or fibrinolytics may be required in the presence of more serious coagulation disorders.

Other medications: changes related to the metabolic syndrome often provoke other disorders, such as increased uric acid levels (hyperuricemia), increased creatinine levels, changes in liver enzymes, etc., therefore, they are prescribed on a case-by-case basis as appropriate additional drug therapy.

Drug therapy, especially in the case of incorrect use (irrational combination of drugs, inappropriate doses, unsuitable drugs), carries the risk of side effects of varying severity and the danger of drug interactions. Patients should be informed in advance about the risks and benefits of medications and about some of the most common side effects.

In case of serious side effects, allergic reactions, toxic reactions, and so on, it is necessary to consult a doctor in a timely manner and stop drug therapy.

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